Anti cancer drugs

Azel 40mg tablets are containing an active substance known as Enzalutamide, which has anti-tumor activity by exhibiting androgen receptor inhibitory activity. Azel 40mg is a non steroidal anti-androgen drug; by inhibiting the androgen synthesis and expels anti-neoplastic activity against prostate tumor.

PRODUCT DETAILS

Brand name                  Azel
Active substance          Enzalutamide
Strength                       40MG
Manufactured by          Dr.Reddys Laboratories
Pack                             28 capsules

MECHANISM OF ACTION

Androgen is a male hormone; testosterone is a one of the hormone secreted from androgen which is responsible for growth of the tumor cells present in the prostate glands. Azel 40 mg tablets are comprises of Enzalutamide which acts by inhibiting the binding of androgen into androgen receptor site. This inhibition leads to interfere with signal transduction of receptors and causes growth retardation. The active metabolite of Enzalutamide is N-desmethyl Enzalutamide which is similar to parent form. Azel exhibits anti-neoplastic effect by reducing the cell proliferation leads to cell death and reduce the tumor cell volume.

PREGNANCY

The pregnancy category of Enzalutamide X, which means it, may cause fetal harm even to death. Azel 40mg should not be recommended in pregnancy conditions.

LACTATION

Breast feeding should not be suggested.

PEDIATRIC

The potency and effectiveness of Azel 40mg capsules should not be evaluated in pediatric patients. In renal & hepatic damaged patients, the dosage adjustment of Azel capsules should not be suggested.

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